BLASTX 2.2.6 [Apr-09-2003] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= QCH30c02.yg.2.1 (722 letters) Database: /db/trembl-ebi/tmp/swall 1,165,242 sequences; 374,381,506 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sptr|Q8S566|Q8S566 Guanine nucleotide-exchange protein GEP1. 260 1e-68 sw|Q42510|EM30_ARATH Pattern formation protein EMB30. 243 2e-63 sptr|Q9FLY5|Q9FLY5 Pattern formation protein. 189 2e-47 sptr|Q9XTF0|Q9XTF0 C24H11.7 protein. 100 1e-20 sw|Q9R1D7|GBF1_CRIGR Golgi-specific brefeldin A-resistance guani... 100 1e-20 sw|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guani... 99 7e-20 sptrnew|EAA00837|EAA00837 EbiP9614 (Fragment). 86 4e-16 sptr|Q9V696|Q9V696 CG8487 protein. 73 4e-12 sptr|Q8ML25|Q8ML25 CG8487-PA. 73 4e-12 sptr|Q9VJW1|Q9VJW1 CG7578 protein (BG:DS00797.7 protein) (LD2917... 58 1e-07 sptr|Q8IP64|Q8IP64 CG7578-PB. 58 1e-07 sptr|Q8S565|Q8S565 Guanine nucleotide-exchange protein GEP2. 55 1e-06 sptrnew|EAA14874|EAA14874 ENSANGP00000006433 (Fragment). 52 9e-06 sptrnew|EAA33457|EAA33457 Hypothetical protein. 51 1e-05 sptr|Q8LN59|Q8LN59 Putative apical-basal pattern formation protein. 51 2e-05 sptr|Q9LPC5|Q9LPC5 F22M8.9 protein. 50 3e-05 sptr|O65490|O65490 Hypothetical 191.5 kDa protein. 49 6e-05 sptr|Q9XGN9|Q9XGN9 Similar to SEC7 protein. 49 8e-05 sptrnew|AAP04588|AAP04588 Brefeldin A-inhibited guanine nucleoti... 48 1e-04 sptr|Q9LZX8|Q9LZX8 Guanine nucleotide exchange factor-like protein. 47 2e-04 sw|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-ex... 47 2e-04 sptr|Q9SZM0|Q9SZM0 Guanine nucleotide-exchange protein-like. 46 4e-04 sw|O46382|BIG1_BOVIN Brefeldin A-inhibited guanine nucleotide-ex... 45 9e-04 sw|Q9Y6D6|BIG1_HUMAN Brefeldin A-inhibited guanine nucleotide-ex... 45 0.001 sptr|Q876I5|Q876I5 GEA2 (Fragment). 41 0.013 sw|Q9UT02|SC71_SCHPO Protein transport protein sec71. 41 0.013 sptr|Q87IE7|Q87IE7 Iron(III) ABC transporter, permease protein. 39 0.048 sptr|Q96X17|Q96X17 Sec7p. 39 0.062 sptr|Q9P7R8|Q9P7R8 Putative guanine-nucleotide exchange factor w... 38 0.11 sw|P39993|GEA2_YEAST ARF guanine-nucleotide exchange factor 2. 38 0.14
>sptr|Q8S566|Q8S566 Guanine nucleotide-exchange protein GEP1. Length = 1175 Score = 260 bits (664), Expect = 1e-68 Identities = 129/226 (57%), Positives = 165/226 (73%), Gaps = 3/226 (1%) Frame = -2 Query: 670 ELXXXXXXXXIXXXXEQXAGXXEXSFSRWVXLXXXSKXXSMYIACSSYPFLDHDMFSVMA 491 EL I EQ G E S SRW+ L SK S+YI S PFLDHDMF++M+ Sbjct: 463 ELYHSICRNEIKTTPEQGMGYFEMSPSRWIDLMRKSKSTSLYIVGDSQPFLDHDMFAIMS 522 Query: 490 GPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALSKFTTLLTTS 311 GPT+AA++VVFD+ EHEEVL C+DGFL VAK++AF+HL DVL+DLVV+L KFTTLL TS Sbjct: 523 GPTIAAIAVVFDHSEHEEVLLACVDGFLGVAKISAFHHLEDVLDDLVVSLCKFTTLLNTS 582 Query: 310 YIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDCILRLHKIGLLPGPLTGD 131 +++PVTAFG+D KAR+ATE +FTIA YGD+IR+GWRN++DCILRLHK+GLLP + D Sbjct: 583 LVEEPVTAFGDDLKARLATETLFTIANRYGDYIRTGWRNVLDCILRLHKLGLLPARVASD 642 Query: 130 TADDQDSSSKSLPGK---LASSAPQVLPISTSRKTYGLMGRFSQLL 2 ADD + S++++ GK + S + + T RK+ GLMGRFSQLL Sbjct: 643 AADDSEVSAETVQGKPTHSSISTSHIPVMGTPRKSSGLMGRFSQLL 688 >sw|Q42510|EM30_ARATH Pattern formation protein EMB30. Length = 1451 Score = 243 bits (619), Expect = 2e-63 Identities = 125/226 (55%), Positives = 161/226 (71%), Gaps = 3/226 (1%) Frame = -2 Query: 670 ELXXXXXXXXIXXXXEQXAGXXEXSFSRWVXLXXXSKXXSMYIACSSYPFLDHDMFSVMA 491 EL I EQ AG E + SRW+ L SK + YI S +LDHDMF++M+ Sbjct: 735 ELFHSICNNEIRTTPEQGAGFPEMTPSRWIDLMHKSKKTAPYILADSRAYLDHDMFAIMS 794 Query: 490 GPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALSKFTTLLTTS 311 GPT+AA+SVVFD+ EHE+V CIDGFL++AK++A +HL DVL+DLVV+L KFTTLL S Sbjct: 795 GPTIAAISVVFDHAEHEDVYQTCIDGFLAIAKISACHHLEDVLDDLVVSLCKFTTLLNPS 854 Query: 310 YIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDCILRLHKIGLLPGPLTGD 131 +D+PV AFG+D KARMAT +FTIA YGD+IR+GWRNI+DCILRLHK+GLLP + D Sbjct: 855 SVDEPVLAFGDDAKARMATITIFTIANKYGDYIRTGWRNILDCILRLHKLGLLPARVASD 914 Query: 130 TADDQDSSSKSLPGK-LAS--SAPQVLPISTSRKTYGLMGRFSQLL 2 AD+ + SS+ GK LA+ S+ + + T R++ GLMGRFSQLL Sbjct: 915 AADESEHSSEQGQGKPLANSLSSAHLQSMGTPRRSSGLMGRFSQLL 960 >sptr|Q9FLY5|Q9FLY5 Pattern formation protein. Length = 1443 Score = 189 bits (481), Expect = 2e-47 Identities = 97/224 (43%), Positives = 136/224 (60%), Gaps = 5/224 (2%) Frame = -2 Query: 670 ELXXXXXXXXIXXXXEQXAGXXEXSFSRWVXLXXXSKXXSMYIACSSYPFLDHDMFSVMA 491 E+ I ++ G + SRW+ + SK S YI C + LD DMF +++ Sbjct: 735 EIYHSIRHSEIQMDEDKGTGFQLMTASRWISVIYKSKETSPYIQCDAASHLDRDMFYIVS 794 Query: 490 GPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALSKFTTLLTTS 311 GPT+AA SVVF+ E E+VL CIDG L++AKL+A+YHL VL+DLVV+L KFT Sbjct: 795 GPTIAATSVVFEQAEQEDVLRRCIDGLLAIAKLSAYYHLNSVLDDLVVSLCKFTPFFAPL 854 Query: 310 YIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDCILRLHKIGLLPGPLTGD 131 D+ V GED +ARMATEAVF IA YGD+I +GW+NI++C+L L+K+ +LP + D Sbjct: 855 SADEAVLVLGEDARARMATEAVFLIANKYGDYISAGWKNILECVLSLNKLHILPDHIASD 914 Query: 130 TADDQDSSSKSLPGKLASSAP-----QVLPISTSRKTYGLMGRF 14 ADD + S+ +L + S+ P Q P + RK+ +GRF Sbjct: 915 AADDPELSTSNLEQEKPSANPVPVVSQSQPSAMPRKSSSFIGRF 958 >sptr|Q9XTF0|Q9XTF0 C24H11.7 protein. Length = 1820 Score = 100 bits (250), Expect = 1e-20 Identities = 56/151 (37%), Positives = 84/151 (55%), Gaps = 24/151 (15%) Frame = -2 Query: 517 DHDMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALS 338 DHD+F+V GP VAA+S VFD EHE++L + G+ AK+AA+Y + +V ++L + L Sbjct: 883 DHDLFAVCWGPAVAALSYVFDKSEHEQILQKALTGYRKCAKIAAYYGMKEVFDNLCIHLC 942 Query: 337 KFTTLLT---------------------TSYIDDP---VTAFGEDTKARMATEAVFTIAT 230 KFTTL + S+ P AFGE+ KA++AT +F + Sbjct: 943 KFTTLTSMRDGGAGGGADEDVDLSAAALLSHSSSPEAVALAFGENHKAQLATRTLFYLVH 1002 Query: 229 VYGDHIRSGWRNIIDCILRLHKIGLLPGPLT 137 G+ +R GWRN+ + +L+L + LLP LT Sbjct: 1003 ENGNILREGWRNLFEALLQLFRARLLPAELT 1033 >sw|Q9R1D7|GBF1_CRIGR Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1). Length = 1856 Score = 100 bits (250), Expect = 1e-20 Identities = 51/123 (41%), Positives = 80/123 (65%) Frame = -2 Query: 517 DHDMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALS 338 D D+F++ GPT+AA+S VFD E ++ I GF A ++A Y L DV ++L+++L Sbjct: 921 DLDLFTMTWGPTIAALSYVFDKSIEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLC 980 Query: 337 KFTTLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDCILRLHKIG 158 KFT L + S I++ T FG + KA +A + VF +A +GD +R GW+NI++ +L+L + Sbjct: 981 KFTALSSES-IENLPTVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAVLQLFRAQ 1039 Query: 157 LLP 149 LLP Sbjct: 1040 LLP 1042 >sw|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1). Length = 1859 Score = 98.6 bits (244), Expect = 7e-20 Identities = 50/123 (40%), Positives = 80/123 (65%) Frame = -2 Query: 517 DHDMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALS 338 D D+F++ GPT+AA+S VFD E ++ I GF A ++A Y L DV ++L+++L Sbjct: 923 DLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLC 982 Query: 337 KFTTLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDCILRLHKIG 158 KFT L + S I++ + FG + KA +A + VF +A +GD +R GW+NI++ +L+L + Sbjct: 983 KFTALSSES-IENLPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQ 1041 Query: 157 LLP 149 LLP Sbjct: 1042 LLP 1044 >sptrnew|EAA00837|EAA00837 EbiP9614 (Fragment). Length = 1285 Score = 85.9 bits (211), Expect = 4e-16 Identities = 52/134 (38%), Positives = 81/134 (60%), Gaps = 5/134 (3%) Frame = -2 Query: 526 PFLDHDMFSVMAGPTVAAVSVVFD-NVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLV 350 P D +++ V+ G T+AA+S VFD ++++ + I GF+ A +AA + L + LV Sbjct: 689 PQHDRELYRVIQGSTLAALSFVFDKSLDNASLYQKAIGGFMKSAAIAAHFQLHGDFDALV 748 Query: 349 VALSKFTTLLTTSYID-DPVTA---FGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDC 182 + L KFTTLLT D +TA FG++ KA++A VF + +GD +R GWR+ +D Sbjct: 749 LTLCKFTTLLTPPPNDAHEITASVMFGQNVKAQLAMRTVFGLIHEHGDCMREGWRHTMDV 808 Query: 181 ILRLHKIGLLPGPL 140 +L+L K+ LLP L Sbjct: 809 LLQLFKLKLLPKAL 822 >sptr|Q9V696|Q9V696 CG8487 protein. Length = 1983 Score = 72.8 bits (177), Expect = 4e-12 Identities = 48/145 (33%), Positives = 79/145 (54%), Gaps = 9/145 (6%) Frame = -2 Query: 547 YIACSSYPFLDHDMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGD 368 Y+ +SY D ++F+++ G +++A+S +FD E + GF A ++A Y+L Sbjct: 862 YVHDASY---DVEIFNIVWGASLSALSFMFDK-STETGYQRTLAGFSKSAAISAHYNLHS 917 Query: 367 VLNDLVVALSKFTTLLTTSYIDDPVTA---------FGEDTKARMATEAVFTIATVYGDH 215 + LV+ L KFTTLL++ +P A FG + KA+ A VF + YGD Sbjct: 918 DFDALVLTLCKFTTLLSSVEQHEPAPANNETQQAVNFGLNGKAQAAMRTVFLLVHDYGDC 977 Query: 214 IRSGWRNIIDCILRLHKIGLLPGPL 140 +R W++I+D L+L ++ LLP L Sbjct: 978 LRESWKHILDLYLQLFRLKLLPKSL 1002 >sptr|Q8ML25|Q8ML25 CG8487-PA. Length = 1740 Score = 72.8 bits (177), Expect = 4e-12 Identities = 48/145 (33%), Positives = 79/145 (54%), Gaps = 9/145 (6%) Frame = -2 Query: 547 YIACSSYPFLDHDMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGD 368 Y+ +SY D ++F+++ G +++A+S +FD E + GF A ++A Y+L Sbjct: 862 YVHDASY---DVEIFNIVWGASLSALSFMFDK-STETGYQRTLAGFSKSAAISAHYNLHS 917 Query: 367 VLNDLVVALSKFTTLLTTSYIDDPVTA---------FGEDTKARMATEAVFTIATVYGDH 215 + LV+ L KFTTLL++ +P A FG + KA+ A VF + YGD Sbjct: 918 DFDALVLTLCKFTTLLSSVEQHEPAPANNETQQAVNFGLNGKAQAAMRTVFLLVHDYGDC 977 Query: 214 IRSGWRNIIDCILRLHKIGLLPGPL 140 +R W++I+D L+L ++ LLP L Sbjct: 978 LRESWKHILDLYLQLFRLKLLPKSL 1002 >sptr|Q9VJW1|Q9VJW1 CG7578 protein (BG:DS00797.7 protein) (LD29171p). Length = 1653 Score = 58.2 bits (139), Expect = 1e-07 Identities = 47/178 (26%), Positives = 85/178 (47%), Gaps = 7/178 (3%) Frame = -2 Query: 535 SSYPFLDH--DMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVL 362 +S L+H MF + P +AA SV + + E+ T C+DG ++A +H+ Sbjct: 823 TSAKHLEHVRPMFKMAWTPFLAAFSVGLQDCDDPEIATLCLDGIRCAIRIACIFHMSLER 882 Query: 361 NDLVVALSKFTTLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDC 182 + V AL++FT L S I++ + A DT + + +A G+++ S W +I+ C Sbjct: 883 DAYVQALARFTLLNANSPINE-MKAKNIDT-----IKTLIMVAHTDGNYLGSSWLDIVKC 936 Query: 181 ILRLH-----KIGLLPGPLTGDTADDQDSSSKSLPGKLASSAPQVLPISTSRKTYGLM 23 I +L G+ P L+G +DS + S+ + ++ Q + ++ R G M Sbjct: 937 ISQLELAQLIGTGVRPQFLSGAQTTLKDSLNPSVKEHIGETSSQSVVVAVDRIFTGSM 994 >sptr|Q8IP64|Q8IP64 CG7578-PB. Length = 1614 Score = 58.2 bits (139), Expect = 1e-07 Identities = 47/178 (26%), Positives = 85/178 (47%), Gaps = 7/178 (3%) Frame = -2 Query: 535 SSYPFLDH--DMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVL 362 +S L+H MF + P +AA SV + + E+ T C+DG ++A +H+ Sbjct: 823 TSAKHLEHVRPMFKMAWTPFLAAFSVGLQDCDDPEIATLCLDGIRCAIRIACIFHMSLER 882 Query: 361 NDLVVALSKFTTLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDC 182 + V AL++FT L S I++ + A DT + + +A G+++ S W +I+ C Sbjct: 883 DAYVQALARFTLLNANSPINE-MKAKNIDT-----IKTLIMVAHTDGNYLGSSWLDIVKC 936 Query: 181 ILRLH-----KIGLLPGPLTGDTADDQDSSSKSLPGKLASSAPQVLPISTSRKTYGLM 23 I +L G+ P L+G +DS + S+ + ++ Q + ++ R G M Sbjct: 937 ISQLELAQLIGTGVRPQFLSGAQTTLKDSLNPSVKEHIGETSSQSVVVAVDRIFTGSM 994 >sptr|Q8S565|Q8S565 Guanine nucleotide-exchange protein GEP2. Length = 1789 Score = 54.7 bits (130), Expect = 1e-06 Identities = 46/172 (26%), Positives = 75/172 (43%), Gaps = 9/172 (5%) Frame = -2 Query: 508 MFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALSKFT 329 M V P +AA SV D + E V++ C++GF S + A + + V +L+KFT Sbjct: 895 MVEVCWAPMLAAFSVPLDQSDDEIVISQCLEGFRSAIHVTAAMSMKTQRDAFVTSLAKFT 954 Query: 328 TLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDCILR---LHKIG 158 +L + + I K A +A+ IA G++++ W +I+ C+ R LH +G Sbjct: 955 SLHSAADIKQ---------KNIEAIKAILLIADEDGNYLQEAWEHILTCVSRFENLHLVG 1005 Query: 157 LLPGP------LTGDTADDQDSSSKSLPGKLASSAPQVLPISTSRKTYGLMG 20 P L D + S+ L +P +P S R +Y G Sbjct: 1006 EGAPPDATFFALQQPDLDKSKQAKSSILPVLKKKSPNTVPAS-KRGSYDSAG 1056 >sptrnew|EAA14874|EAA14874 ENSANGP00000006433 (Fragment). Length = 1522 Score = 51.6 bits (122), Expect = 9e-06 Identities = 44/164 (26%), Positives = 78/164 (47%), Gaps = 9/164 (5%) Frame = -2 Query: 535 SSYPFLDH--DMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVL 362 +S L+H MF + +AA SV + + E+ + C+DG ++A +H+ Sbjct: 743 TSAKHLEHVRPMFKMAWTSFLAAFSVGLQDCDDPEIASLCLDGIRCAVRIACIFHMSLER 802 Query: 361 NDLVVALSKFTTLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDC 182 + V AL++FT L S I++ + A DT + + +A G+++ S W +I+ C Sbjct: 803 DAYVQALARFTLLTANSPINE-MKAKNIDT-----IKTLIMVAHTDGNYLGSSWLDIVKC 856 Query: 181 ILRLH-----KIGLLPGPLTGDTA--DDQDSSSKSLPGKLASSA 71 I L G+ P L+G + D D S+K G+ +S + Sbjct: 857 ISHLELAQLIGTGVRPEFLSGPASHRDTLDPSAKEHIGETSSQS 900 >sptrnew|EAA33457|EAA33457 Hypothetical protein. Length = 1626 Score = 51.2 bits (121), Expect = 1e-05 Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 17/163 (10%) Frame = -2 Query: 586 WVXLXXXSKXXSMYIACSSYPFLDHDMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFL 407 W L ++ + C + + D D+F+ ++ + VF + + V I GF Sbjct: 872 WKELLLKTESAGPLVLCDTNIY-DADIFNTTWNAIISCLFFVFMSATDDTVYARVITGFD 930 Query: 406 SVAKLAAFYHLGDVLNDLVVALSKFTTLLTTSY-----------------IDDPVTAFGE 278 A++A Y + L++LV LS +TL + S + + FG Sbjct: 931 ECARIATKYGNSEALDELVYRLSLISTLSSESLSNTQLNTEVQVGENSVMVSELAVKFGR 990 Query: 277 DTKARMATEAVFTIATVYGDHIRSGWRNIIDCILRLHKIGLLP 149 D + ++AT +F + T IR+ W+ I+ L L L+P Sbjct: 991 DVRPQLATLVLFRVVTGSEHIIRNSWKYIVRIWLNLFVNSLIP 1033 >sptr|Q8LN59|Q8LN59 Putative apical-basal pattern formation protein. Length = 351 Score = 50.8 bits (120), Expect = 2e-05 Identities = 27/78 (34%), Positives = 44/78 (56%), Gaps = 7/78 (8%) Frame = -2 Query: 214 IRSGWRNIIDCILRLHKIGLLPGPLTGDT--ADDQDSSSKSLPGKLASSAPQVLPIS--- 50 +R+ W+N++DC+L+L + LLP + A SS++ L + S + + P S Sbjct: 13 VRAAWKNVVDCLLKLKRFKLLPPSVVDQDGGASTVSSSTERLGHRAKSESGVIFPSSHRG 72 Query: 49 --TSRKTYGLMGRFSQLL 2 TSR +G++GRFSQ L Sbjct: 73 AGTSRHVFGMIGRFSQFL 90 >sptr|Q9LPC5|Q9LPC5 F22M8.9 protein. Length = 1750 Score = 50.1 bits (118), Expect = 3e-05 Identities = 37/137 (27%), Positives = 62/137 (45%) Frame = -2 Query: 562 KXXSMYIACSSYPFLDHDMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAF 383 K S+Y A S L M V P +AA SV D + + T C++GF + + Sbjct: 850 KSESVYYAASDVIILRF-MVEVCWAPMLAAFSVPLDQSDDAVITTLCLEGFHHAIHVTSV 908 Query: 382 YHLGDVLNDLVVALSKFTTLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSG 203 L + V +L+KFT+L + + I K A +A+ +A G++++ Sbjct: 909 MSLKTHRDAFVTSLAKFTSLHSPADIKQ---------KNIEAIKAIVKLAEEEGNYLQDA 959 Query: 202 WRNIIDCILRLHKIGLL 152 W +I+ C+ R + LL Sbjct: 960 WEHILTCVSRFEHLHLL 976 >sptr|O65490|O65490 Hypothetical 191.5 kDa protein. Length = 1711 Score = 48.9 bits (115), Expect = 6e-05 Identities = 31/119 (26%), Positives = 53/119 (44%) Frame = -2 Query: 508 MFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALSKFT 329 + V GP +AA SV D + + C+ GF + A + + V +++KFT Sbjct: 826 ILEVSWGPMLAAFSVTIDQSDDRLATSLCLQGFRYAVHVTAVMGMQTQRDAFVTSMAKFT 885 Query: 328 TLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDCILRLHKIGLL 152 L + + K A +A+ TIA G+H+ W +I+ C+ R+ + LL Sbjct: 886 NLHCAADMKQ---------KNVDAVKAIITIAIEDGNHLHGSWEHILTCLSRIEHLQLL 935 >sptr|Q9XGN9|Q9XGN9 Similar to SEC7 protein. Length = 1687 Score = 48.5 bits (114), Expect = 8e-05 Identities = 35/144 (24%), Positives = 62/144 (43%), Gaps = 7/144 (4%) Frame = -2 Query: 508 MFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALSKFT 329 M V P +AA SV D + + + C+ GF S + A + + V +++KFT Sbjct: 801 MMEVCWAPMMAAFSVTLDQSDDKAATSQCLQGFRSAVHVTAVMCMQTQRDAFVTSVAKFT 860 Query: 328 TLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDCILRLHKIGLL- 152 L + + K A +A+ +IA GD+++ W +++ C+ R + LL Sbjct: 861 YLHCAADMKQ---------KNVDAVKAIISIAIEDGDYLQDSWEHVLTCLSRFEHLHLLG 911 Query: 151 ------PGPLTGDTADDQDSSSKS 98 LT + +D + KS Sbjct: 912 EGAPTDASFLTVPLVESEDKTQKS 935 >sptrnew|AAP04588|AAP04588 Brefeldin A-inhibited guanine nucleotide-exchange factor 2. Length = 1791 Score = 48.1 bits (113), Expect = 1e-04 Identities = 33/130 (25%), Positives = 62/130 (47%), Gaps = 2/130 (1%) Frame = -2 Query: 535 SSYPFLDH--DMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVL 362 +S LDH MF ++ P +AA S+ N + EV + C++G ++A + + Sbjct: 889 TSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAVRIACIFGMQLER 948 Query: 361 NDLVVALSKFTTLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDC 182 + V AL++F+ L +S I + K + + T+A G+++ + W I+ C Sbjct: 949 DAYVQALARFSLLTASSSITEM------KQKNIDTIKTLITVAHTDGNYLGNSWHEILKC 1002 Query: 181 ILRLHKIGLL 152 I +L L+ Sbjct: 1003 ISQLELAQLI 1012 >sptr|Q9LZX8|Q9LZX8 Guanine nucleotide exchange factor-like protein. Length = 1793 Score = 47.0 bits (110), Expect = 2e-04 Identities = 41/160 (25%), Positives = 68/160 (42%), Gaps = 5/160 (3%) Frame = -2 Query: 562 KXXSMYIACSSYPFLDHDMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAF 383 K S Y A + L M P +AA SV D + V+ C++GF + Sbjct: 859 KSESTYYAATDVVILRF-MIEACWAPMLAAFSVPLDQSDDLIVINICLEGFHHAIHATSL 917 Query: 382 YHLGDVLNDLVVALSKFTTLLTTSYIDDPVTAFGEDTKAR--MATEAVFTIATVYGDHIR 209 + + V +L+KFT+L + + D K R A +A+ +A G++++ Sbjct: 918 MSMKTHRDAFVTSLAKFTSLHSPA-----------DIKQRNIEAIKAILRLADEEGNYLQ 966 Query: 208 SGWRNIIDCILRLHKIGLLPGPLTGDT---ADDQDSSSKS 98 W +I+ C+ R ++ LL D A Q+ S KS Sbjct: 967 DAWEHILTCVSRFEQLHLLGEGAPPDATFFASKQNESEKS 1006 >sw|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2). Length = 1785 Score = 47.0 bits (110), Expect = 2e-04 Identities = 34/134 (25%), Positives = 63/134 (47%), Gaps = 6/134 (4%) Frame = -2 Query: 535 SSYPFLDH--DMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVL 362 +S LDH MF ++ P +AA S+ N + EV + C++G ++A + + Sbjct: 882 TSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLER 941 Query: 361 NDLVVALSKFTTLLTTSYIDDPVTAFGEDTKARMAT----EAVFTIATVYGDHIRSGWRN 194 + V AL++F+ L +S I TK + + + T+A G+++ + W Sbjct: 942 DAYVQALARFSLLTASSSI----------TKMKQKNIDTIKTLITVAHTDGNYLGNSWHE 991 Query: 193 IIDCILRLHKIGLL 152 I+ CI +L L+ Sbjct: 992 ILKCISQLELAQLI 1005 >sptr|Q9SZM0|Q9SZM0 Guanine nucleotide-exchange protein-like. Length = 1643 Score = 46.2 bits (108), Expect = 4e-04 Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 2/121 (1%) Frame = -2 Query: 508 MFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALSKFT 329 M V GP +AA SV D + C+ GF + A + + V +++KFT Sbjct: 743 MVEVSWGPMLAAFSVTLDQSDDRLAAVECLRGFRYAVHVTAVMGMQTQRDAFVTSMAKFT 802 Query: 328 TLLTTSYIDDPVTAFGEDTKARMATE--AVFTIATVYGDHIRSGWRNIIDCILRLHKIGL 155 L + + + E A+ +IA G+H++ W +I+ C+ R+ + L Sbjct: 803 NLHCAGDMKQKNVDAVKKASPSLDGEKHAIISIAIEDGNHLQDAWEHILTCLSRIEHLQL 862 Query: 154 L 152 L Sbjct: 863 L 863 >sw|O46382|BIG1_BOVIN Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor). Length = 1849 Score = 45.1 bits (105), Expect = 9e-04 Identities = 33/130 (25%), Positives = 61/130 (46%), Gaps = 2/130 (1%) Frame = -2 Query: 535 SSYPFLDH--DMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVL 362 +S L+H MF + P +AA SV + + EV + C++G ++A + + Sbjct: 937 TSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAIRIACIFSIQLER 996 Query: 361 NDLVVALSKFTTLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDC 182 + V AL++FT L +S I + K + + T+A G+++ + W I+ C Sbjct: 997 DAYVQALARFTLLTVSSGITE------MKQKNIDTIKTLITVAHTDGNYLGNSWHEILKC 1050 Query: 181 ILRLHKIGLL 152 I +L L+ Sbjct: 1051 ISQLELAQLI 1060 >sw|Q9Y6D6|BIG1_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor). Length = 1849 Score = 44.7 bits (104), Expect = 0.001 Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SSYPFLDH--DMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVL 362 +S L+H MF + P +AA SV + + EV + C++G ++A + + Sbjct: 937 TSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAIRIACIFSIQLER 996 Query: 361 NDLVVALSKFTTLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDC 182 + V AL++FT L +S I + K + + T+A G+++ + W I+ C Sbjct: 997 DAYVQALARFTLLTVSSGITE------MKQKNIDTIKTLITVAHTDGNYLGNSWHEILKC 1050 Query: 181 ILRL 170 I +L Sbjct: 1051 ISQL 1054 >sptr|Q876I5|Q876I5 GEA2 (Fragment). Length = 667 Score = 41.2 bits (95), Expect = 0.013 Identities = 41/196 (20%), Positives = 82/196 (41%), Gaps = 33/196 (16%) Frame = -2 Query: 490 GPTVAAVSV-VFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALSKFTTLLTT 314 GP++ + ++ + + T I + +AAF+ D+ ND++ +++K TTL+++ Sbjct: 6 GPSIVSTLFNIYVVASDDHISTRMITSLDKCSYIAAFFDFKDLFNDILNSIAKGTTLVSS 65 Query: 313 SYIDDPVT---AFGEDTKARMATEAVFTIATVYGDHIRSG-------------------- 203 S+ D+ T +G ++ E T+ V D +R G Sbjct: 66 SHDDELSTLAFEYGPMPLVQITFEDTNTVIPVSTDAVRFGRSFKGQLNTVVLFRIIRRNK 125 Query: 202 ---------WRNIIDCILRLHKIGLLPGPLTGDTADDQDSSSKSLPGKLASSAPQVLPIS 50 W NI++ IL L + +LP + D + G L +P++ I+ Sbjct: 126 DPKIFSKKLWSNIVNIILTLFEDLILPPDIF------PDLQKRLKLGNLPKPSPEI-SIN 178 Query: 49 TSRKTYGLMGRFSQLL 2 S+++ G + F+ L Sbjct: 179 KSKESKGFLSTFASYL 194 >sw|Q9UT02|SC71_SCHPO Protein transport protein sec71. Length = 1811 Score = 41.2 bits (95), Expect = 0.013 Identities = 34/159 (21%), Positives = 67/159 (42%), Gaps = 3/159 (1%) Frame = -2 Query: 508 MFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALSKFT 329 MF + P +AA S ++ +DGF + F+ + N + L+KFT Sbjct: 971 MFEAVWMPILAAFSEPLQLSSDPALIQLSLDGFRLAMNVIFFFSMDLPRNAFMQTLTKFT 1030 Query: 328 TLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDCILRLHKIGLLP 149 L TS + A + + I+ +GD +R W++++ CI +L ++ L+ Sbjct: 1031 HLNNTSELK---------WTNMHALKTLLEISLAHGDKLRDSWKDVLLCISQLERVQLIS 1081 Query: 148 GPLTGDTADDQDSSS---KSLPGKLASSAPQVLPISTSR 41 + ++ D ++ KSL + S + + S+ Sbjct: 1082 AGVDINSLPDVSTTKPLRKSLDKNIRQSRSGSISLKHSK 1120 >sptr|Q87IE7|Q87IE7 Iron(III) ABC transporter, permease protein. Length = 316 Score = 39.3 bits (90), Expect = 0.048 Identities = 35/125 (28%), Positives = 57/125 (45%) Frame = -2 Query: 499 VMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALSKFTTLL 320 V+AG +A S+VF + H +LT I GF A Y L VL +V+ +TL+ Sbjct: 46 VLAGVAIAQSSMVFQTITHNRILTPSIMGF------DALYVLTQVL--IVLLFGGLSTLV 97 Query: 319 TTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDCILRLHKIGLLPGPL 140 Y++ + A F++ ++G + G RN+I +L +GL+ G L Sbjct: 98 LNIYVNFTIAA---------CIMVAFSL-LLFGFYFSKGSRNLITLLL----VGLIFGQL 143 Query: 139 TGDTA 125 + A Sbjct: 144 FSNVA 148 >sptr|Q96X17|Q96X17 Sec7p. Length = 1772 Score = 38.9 bits (89), Expect = 0.062 Identities = 28/119 (23%), Positives = 48/119 (40%) Frame = -2 Query: 508 MFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALSKFT 329 MF + A ++ F + E+ CI G L+ + + + + V AL +F Sbjct: 938 MFHTLWMSIFAGLTPPFKEYDDEDTTKLCIKGIKLAIHLSCTFDIENARSSFVGALVQFG 997 Query: 328 TLLTTSYIDDPVTAFGEDTKARMATEAVFTIATVYGDHIRSGWRNIIDCILRLHKIGLL 152 L I K A A+ +A GDH+R W+ I+ + ++ +I LL Sbjct: 998 NLHNVEEISP---------KNVDAIHALLNVAVTEGDHLRGSWKEILLSVSQIERIQLL 1047 >sptr|Q9P7R8|Q9P7R8 Putative guanine-nucleotide exchange factor with sec7 domain. Length = 1462 Score = 38.1 bits (87), Expect = 0.11 Identities = 31/134 (23%), Positives = 60/134 (44%), Gaps = 22/134 (16%) Frame = -2 Query: 481 VAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALSKFTTLLTTSY-- 308 +AA+ VF + V ++G ++AA Y L + ++ + +FT L +S Sbjct: 782 MAALIYVFSTATEDTVFYRVVNGIQQATEVAAAYELNEPVDYAIERFCQFTALDPSSVPG 841 Query: 307 --------IDDPVTA-------FGEDTKARMATEAVFTIATVYGDHIRSGWRNIID---C 182 ++D + FG D +A++A +F I++ +G+ I + W ++ C Sbjct: 842 TQLNTAIKVEDRIITVSELSVRFGRDFRAQLALLVLFWISSKFGNIIDASWPLLVQLTIC 901 Query: 181 ILRLHKI--GLLPG 146 + R + I LPG Sbjct: 902 LARNNLIDNSFLPG 915 >sw|P39993|GEA2_YEAST ARF guanine-nucleotide exchange factor 2. Length = 1459 Score = 37.7 bits (86), Expect = 0.14 Identities = 42/204 (20%), Positives = 84/204 (41%), Gaps = 32/204 (15%) Frame = -2 Query: 517 DHDMFSVMAGPTVAAVSVVFDNVEHEEVLTGCIDGFLSVAKLAAFYHLGDVLNDLVVALS 338 D +F + V+ + ++ + + T I + ++AF+ D+ ND++ +++ Sbjct: 806 DRAIFKQVGPSIVSTLFNIYVVASDDHISTRMITSLDKCSYISAFFDFKDLFNDILNSIA 865 Query: 337 KFTTLLTTSYIDD-------------------------PVTA----FGEDTKARMATEAV 245 K TTL+ +S+ D+ PV+ FG K ++ T Sbjct: 866 KGTTLINSSHDDELSTLAFEYGPMPLVQIKFEDTNTEIPVSTDAVRFGRSFKGQLNTVVF 925 Query: 244 FTIATVYGD---HIRSGWRNIIDCILRLHKIGLLPGPLTGDTADDQDSSSKSLPGKLASS 74 F I D + W NI++ IL L++ +L + D S+ L Sbjct: 926 FRIIRRNKDPKIFSKELWLNIVNIILTLYEDLILSPDIFPDLQKRLKLSN------LPKP 979 Query: 73 APQVLPISTSRKTYGLMGRFSQLL 2 +P++ I+ S+++ GL+ F+ L Sbjct: 980 SPEI-SINKSKESKGLLSTFASYL 1002 Database: /db/trembl-ebi/tmp/swall Posted date: Jul 11, 2003 8:27 PM Number of letters in database: 374,381,506 Number of sequences in database: 1,165,242 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 375,124,230 Number of Sequences: 1165242 Number of extensions: 6874777 Number of successful extensions: 18259 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 17752 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 18219 length of database: 374,381,506 effective HSP length: 119 effective length of database: 235,717,708 effective search space used: 28521842668 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
S1: 41 (21.7 bits)